934474-97-2
934474-97-2
Chemical Structure
ADS103317
- CAS No.: 934474-97-2
- Formula:C21H21ClN4O2
- Molecular Weight:396.88
IUPAC Name: 2-(3-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl)quinazolin-6-yl)acetamide
InChIKey: DTCJZJYPMORMJZ-UHFFFAOYSA-N
SMILES: O=C(NC=1C=CC2=NC(=NC(=C2C1)C)N3CCCC3)COC=4C=CC=C(Cl)C4
Biological Activity: ADS103317 is an analog of Afatinib (HY-10261). ADS103317 weakly inhibits MCH-1R. Afatinib is an EGFR inhibitor. ADS103317 can be used in research related to non-small cell lung cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ADS103317 | ADS103317 is an analog of Afatinib (HY-10261). ADS103317 weakly inhibits MCH-1R. Afatinib is an EGFR inhibitor. ADS103317 can be used in research related to non-small cell lung cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Gudala S, et al. Identification and Pharmacological Analysis of High Efficacy Small Molecule Inhibitors of EGF-EGFR Interactions in Clinical Treatment of Non-Small Cell Lung Carcinoma: a Computational Approach. Asian Pac J Cancer Prev. 2015;16(18):8191-8196. [Content Brief]
- [2]. Arienzo R, et al. Quinazoline and benzimidazole MCH-1R antagonists. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. [Content Brief]
Keywords
