99685-66-2
Chemical Structure
Somatostatin RC-102
- CAS No.: 99685-66-2
- Formula:C49H65N11O10S2
- Molecular Weight:1032.25
IUPAC Name: (4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-benzyl-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
InChIKey: SGYDRBBPYPDBRO-WNIOSIORSA-N
SMILES: C(C=1C=2C(NC1)=CC=CC2)[C@H]3NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@@H](NC([C@@H](CC5=CC=CC=C5)N)=O)CSSC[C@@H](C(N[C@@H]([C@@H](C)O)C(N)=O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCCCN)NC3=O)[H]
Biological Activity: Somatostatin RC-102 is an octapeptide analog of Somatostatin. Somatostatin RC-102 inhibits the release of growth hormone and insulin. Somatostatin RC-102 enhances the inhibition of cell migration by increasing the production or activity of LMIF, but exerts no effect on cell migration in the absence of exposure to cardiac antigens or phytohemagglutinin. Somatostatin RC-102 inhibits gastric acid secretion. Somatostatin RC-102 can be used in the research of heart diseases[1][2].
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Somatostatin RC-102 | Somatostatin RC-102 is an octapeptide analog of Somatostatin. Somatostatin RC-102 inhibits the release of growth hormone and insulin. Somatostatin RC-102 enhances the inhibition of cell migration by increasing the production or activity of LMIF, but exerts no effect on cell migration in the absence of exposure to cardiac antigens or phytohemagglutinin. Somatostatin RC-102 inhibits gastric acid secretion. Somatostatin RC-102 can be used in the research of heart diseases. | |||||||||||||||||||||
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References
- [1]. Pawlikowski M, et al. Somatostatin and its analog enhance the formation of human leukocyte migration inhibiting factor: further evidence for immunomodulatory action of somatostatin. Peptides. 1987;8(5):951-2.
- [2]. Cai RZ, et al. Synthesis and biological activity of highly potent octapeptide analogs of somatostatin. Proceedings of the National Academy of Sciences of the United States of America. 1986 Mar;83(6):1896-900.
