2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. CAY10581

CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM.

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CAY10581

CAY10581 Chemical Structure

CAS No. : 1018340-07-2

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CAY10581 Related Antibodies

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Description

CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM[1][2].

IC50 & Target[2]

IDO

55 nM (IC50)

In Vitro

CAY10581 (100 nM; 24 h) abrogates the growth inhibition by IFN-gamma in MSCs[1].
CAY10581 (compound 36) demonstrates minimal impact on T-REx cells viability at 100 μM after 24 h[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAY10581 Related Antibodies

Cell Viability Assay[1]

Cell Line: Mesenchymal stem cells (MSCs)
Concentration: 100 nM
Incubation Time: 24 h post-treatment
Result: Abrogated the growth inhibition by IFN-gamma (50 ng/ml) in MSCs.
Masse moléculaire

363.41

Formule

C22H21NO4
CAS No.
SMILES

O=C1C2=C(C(C3=C1C=CC=C3)=O)[C@@H]([C@@H](C(C)(O2)C)O)NCC4=CC=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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CAY10581 Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAY105811018340-07-2CAY 10581CAY-10581Indoleamine 2,3-Dioxygenase (IDO)PyranonaphthoquinonereversibleuncompetitiveMSCsInhibitorinhibitorinhibit

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Nom du produit:
CAY10581
Cat. No.:
HY-113568
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