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Art. -Nr.: HY-W1049002

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3-Arm PEG2000-Mal

3-Arm PEG2000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG2000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.

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Molecular Weight:2000 (Average)

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Arm PEG2000-Mal Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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Biologische Aktivität

Beschreibung

In Vitro

The structure of PEG-Alkyne comprises two key components that work synergistically:
Maleimide: Located at the end of the PEG chain, it acts as a reaction interface, enabling specific Michael addition reactions with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) to achieve targeting or tracing functions.
PEG chain: Serving as a hydrophilic spacer arm, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 2000 (Average)
SMILES

O=C(OCCOCC(COCCOC(CCN1C(C=CC1=O)=O)=O)(CC)COCCOC(CCN2C(C=CC2=O)=O)=O)CCN3C(C=CC3=O)=O.[n].[n].[n]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.