8(S)-HETE
Based on 1 Customer Validation
8(S)-HETE (8(S)-Hydroxyeicosatetraenoic acid) is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
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- Reinheit: 99.9%
- CAS. Nr.: 98462-03-4
- Formel: C20H32O3
- Molecular Weight:320.47
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Speicherung:
Solution, -20°C, 2 years
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 98462-03-4
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Appearance Liquid
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Molecular Weight 320.47
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Formel C20H32O3
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C/C=C/C=C\[C@H](C/C=C\CCCC(O)=O)O
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Synonyms
8(S)-Hydroxyeicosatetraenoic acid
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Solution, -20°C, 2 years
Reinheit & Dokumentation
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Data Sheet (261 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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