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Art. -Nr.: HY-14541S3

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Olanzapine-d₁₅

(Synonyms: LY170053-d₁₅)

Olanzapine-d₁₅ (LY170053-d₁₅) is the deuterium labeled Olanzapine (HY-14541). Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (K_i = 7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (K_i = 11 to 31 nM), muscarinic M1-5 (K_i = 1.9-25 nM), and adrenergic α1 receptor (K_i = 19 nM). Olanzapine is an atypical antipsychotic.

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CAS. Nr.: 1252611-25-8
Formel: C₁₇H₅D₁₅N₄S
Molecular Weight:327.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Olanzapine-d₁₅ Chemical Structure

CAS. Nr.: 1252611-25-8

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Biologische Aktivität
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Biologische Aktivität

Beschreibung

Alle mAChR Isoform-spezifische Produkte anzeigen :

Alle Dopamine Receptor Isoform-spezifische Produkte anzeigen :

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen :

Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS. Nr. 1252611-25-8
Unlabeled Cas 132539-06-1
Molecular Weight 327.52
Formel C₁₇H₅D₁₅N₄S
SMILES

CC1=CC2=C(S1)NC3=C([2H])C([2H])=C([2H])C([2H])=C3N=C2N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C([2H])([2H])[2H]
Synonyms

LY170053-d₁₅
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.