Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro
- Cell Biochem Biophys. 2025 Sep 27. doi: 10.1007/s12013-025-01916-x.
Affiliations
- 1. Department of Preventive Medicine, School of Medicine, Shihezi University, North 2th Road, Shihezi, 832000, Xinjiang, People's Republic of China.
- 2. Key Laboratory of Xinjiang Endemic and Ethnic Diseases (Ministry of Education), School of Medicine, Shihezi University, Shihezi, Xinjiang, People's Republic of China.
- 3. Department of Preventive Medicine, School of Medicine, Shihezi University, North 2th Road, Shihezi, 832000, Xinjiang, People's Republic of China. [email protected].
- 4. Key Laboratory of Xinjiang Endemic and Ethnic Diseases (Ministry of Education), School of Medicine, Shihezi University, Shihezi, Xinjiang, People's Republic of China. [email protected].
PMID: 41014453
DOI: 10.1007/s12013-025-01916-x
Keywords
Autophagy; Grape seed proanthocyanidin extract (GSPE); Neurotoxicity; Sodium fluoride; mTOR/p70s6k.