Chordin-Like 1 mRNA Therapy for Acute Myocardial Infarction

  • Circulation. 2025 Dec 2;152(22):1586-1589. doi: 10.1161/CIRCULATIONAHA.125.074078.
Mateusz Tomczyk  1 ,  Izabela Kraszewska  #  1 ,  Gang Li  #  1 ,  Matthew John Hayes  2 ,  Luca Venditti  1 ,  Josef Huntington  1 ,  Chun Kit Wong  1 ,  Angelica Cadoni  1 ,  Francesca Bortolotti  3  4 ,  Antonio Mura  3  4 ,  Manendra Pachauri  3  4 ,  Gianfranco Sinagra  5 ,  Mauro Giacca  3  4
Affiliations
  • 1. School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King's College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).
  • 2. Institute of Ophthalmology, University College London, London, United Kingdom (M.J.H.).
  • 3. Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).
  • 4. Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy (F.B., A.M., M.P., M.G.).
  • 5. Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy (G.S.).
  • # Contributed equally.
PMID: 41325441 DOI: 10.1161/CIRCULATIONAHA.125.074078
Keywords
acute myocardial infarction; chordin-like 1 mRNA; lipid nanoparticle; myocardial infarction.
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