p38 MAP Kinase Inhibitor IV
Based on 1 Customer Validation
p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC50s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively.
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- Pureté: 98.0%
- CAS No.: 1638-41-1
- Formule: C12H4Cl6O4S
- Masse moléculaire:456.94
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
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p38α 0.13 μM (IC50) |
p38β 0.55 μM (IC50) |
p38δ 8.63 μM (IC50) |
p38χ 5.47 μM (IC50) |
p38 MAP Kinase Inhibitor IV (MT4) shows IC50 values of 0.13, 0.55, 5.47, and 8.63μM for p38α, β, χ, andδ, respectively. p38 MAP Kinase Inhibitor IV has the suppressive action on the release of TNF-alpha and IL-1beta in PBMC with IC50 values of 22 and 44 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1638-41-1
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Appearance Solid
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Masse moléculaire 456.94
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Formule C12H4Cl6O4S
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Color White to off-white
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SMILES
OC1=C(Cl)C=C(Cl)C(Cl)=C1S(=O)(C2=C(O)C(Cl)=CC(Cl)=C2Cl)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)