Pelitinib (Standard)
Pelitinib (Standard) is the analytical standard of Pelitinib. This product is intended for research and analytical applications. Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC50 of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282, 800, and 1255 nM, respectively.
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- Pureté : 98%
- CAS No.: 257933-82-7
- Formule: C24H23ClFN5O2
- Masse moléculaire:467.92
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-32718
PelitinibSrc Inhibitor -
HY-50898
LapatinibEGFR/HER2 Inhibitor -
HY-32721
NeratinibHER2/EGFR Inhibitor -
HY-50895
GefitinibEGFR Inhibitor -
HY-50896
ErlotinibEGFR Tyrosine Kinase Inhibitor -
HY-50898R
Lapatinib (Standard)EGFR/HER2 Inhibitor -
HY-12008
Erlotinib HydrochlorideEGFR Tyrosine Kinase Inhibitor -
HY-10367
CanertinibEGFR Inhibitor -
HY-10251
BMS-599626HER1/2 Inhibitor -
HY-13524
AG-1478EGFR Inhibitor -
HY-32721R
Neratinib (Standard)HER2/EGFR Inhibitor -
HY-15164A
IcotinibEGFR Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 257933-82-7
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Masse moléculaire 467.92
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Formule C24H23ClFN5O2
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SMILES
N#CC1=C(C2=CC(NC(/C=C/CN(C)C)=O)=C(OCC)C=C2N=C1)NC3=CC(Cl)=C(C=C3)F
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Synonyms
EKB-569 (Standard); WAY-EKB 569 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Torrance CJ, et al. Combinatorial chemoprevention of intestinal neoplasia. Nat Med. 2000 Sep;6(9):1024-8. [Content Brief]
[2]. Nunes M, et al. Phosphorylation of extracellular signal-regulated kinase 1 and 2, protein kinase B, and signal transducer and activator of transcription 3 are differently inhibited by an epidermal growth factor receptor inhibitor, EKB-569, in tumor cells and normal human keratinocytes. Mol Cancer Ther. 2004 Jan;3(1):21-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pelitinib (Standard) Related Classifications
HY-32718R Related Classifications
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