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Cat. No.: HY-158693

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WLB-87848

WLB-87848 is a selective, orally active, and blood-brain barrier (BBB) permeable σ1 receptor agonist with the K_i of 9 nM. WLB-87848 rescues recognition memory impairment.

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CAS No.: 2839205-09-1
Formule: C₁₇H₁₅F₂N₃OS
Masse moléculaire:347.38

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

WLB-87848 Chemical Structure

CAS No.: 2839205-09-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

WLB-87848 is a selective, orally active, and blood-brain barrier (BBB) permeable σ1 receptor agonist with the K_i of 9 nM. WLB-87848 rescues recognition memory impairment^[1].

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Chemical Information

CAS No. 2839205-09-1
Masse moléculaire 347.38
Formule C₁₇H₁₅F₂N₃OS
SMILES

FC(C=CC([C@H](N1C=NC(SC2=C3CCNC2)=C3C1=O)C)=C4)=C4F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Christmann U, et al. WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity. J Med Chem. 2024;67(11):9150-9164. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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WLB-87848

Voir tous les produits spécifiques à Isoform Sigma Receptor

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

WLB-87848 Related Classifications

HY-158693 Related Classifications

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Keywords

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