2. Anti-infection
  3. Bacterial
    Antibiotic
  4. Chlorhexidine diacetate

Chlorhexidine diacetate 

Cat. No.: HY-W013699 Purity: 99.86%
COA Handling Instructions

Chlorhexidine diacetate is a biguanide disinfectant with rapid bactericidal activity against both Gram-positive and Gram-negative organism. The antibacterial effect of chlorhexidine diacetate is related to its action on the bacterial cell membrane and to precipitation of intracellular contents.

For research use only. We do not sell to patients.

Chlorhexidine diacetate Chemical Structure

Chlorhexidine diacetate Chemical Structure

CAS No. : 56-95-1

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Customer Review

Based on 7 publication(s) in Google Scholar

Other Forms of Chlorhexidine diacetate:

Top Publications Citing Use of Products

    Chlorhexidine diacetate purchased from MCE. Usage Cited in: Cancer Res. 2019 Feb 1;79(3):534-545.  [Abstract]

    The half-life of p53 protein is detected in GYS2 overexpressed cells by added with Chlorhexidine (CHX, 20 μg/mL) for different times.

    View All Antibiotic Isoform Specific Products:

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    • Biological Activity

    • Purity & Documentation

    • References

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    Description

    Chlorhexidine diacetate is a biguanide disinfectant with rapid bactericidal activity against both Gram-positive and Gram-negative organism. The antibacterial effect of chlorhexidine diacetate is related to its action on the bacterial cell membrane and to precipitation of intracellular contents[1].

    Clinical Trial
    Molecular Weight

    625.55

    Appearance

    Solid

    Formula

    C26H38Cl2N10O4
    CAS No.
    SMILES

    N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N.CC(O)=O.CC(O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, stored under nitrogen

    *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
    Solvent & Solubility
    In Vitro: 

    Ethanol : 55 mg/mL (87.92 mM; Need ultrasonic)

    H2O : 20 mg/mL (31.97 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.5986 mL 7.9930 mL 15.9859 mL
    5 mM 0.3197 mL 1.5986 mL 3.1972 mL
    10 mM 0.1599 mL 0.7993 mL 1.5986 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2.5 mg/mL (4.00 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 2.5 mg/mL (4.00 mM); Clear solution

    • 3.

      Add each solvent one by one:  10% EtOH    90% corn oil

      Solubility: ≥ 2.5 mg/mL (4.00 mM); Clear solution

    *All of the co-solvents are available by MCE.
    Purity & Documentation

    Purity: 99.86%

    COA (244 KB) HNMR (294 KB) LCMS (267 KB)

    Handling Instructions (2659 KB)
    References
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

    Keywords:

    Chlorhexidine diacetate56-95-1BacterialAntibioticantimicrobialbiguanidedisinfectantGrampositivenegativecellmembraneInhibitorinhibitorinhibit

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