1. Anti-infection
    Metabolic Enzyme/Protease
  2. Bacterial
    Endogenous Metabolite
  3. Coenzyme F420-1

Coenzyme F420-1 (Synonyms: Factor F420-1)

Cat. No.: HY-136497
Handling Instructions

Coenzyme F420-1 (Factor F420-1), a deazaflavin derivative, acts as an important hydride acceptor/donor in the central methanogenic pathway.

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Coenzyme F420-1 Chemical Structure

Coenzyme F420-1 Chemical Structure

CAS No. : 37333-48-5

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Coenzyme F420-1 (Factor F420-1), a deazaflavin derivative, acts as an important hydride acceptor/donor in the central methanogenic pathway[1].

In Vitro

Coenzyme F420 is the central low-redox-potential electron carrier in methanogenic metabolism. Coenzyme F420 is reduced under hydrogen by the action of F420-dependent hydrogenase[2].
Coenzyme F420 acts as a hydride transfer coenzyme for an F420-specific glucose-6-phosphate dehydrogenase (Fgd) in mycobacteria. Coenzyme F420 is found in all methanogenic and certain nonmethanogenic archaea, where it participates in energy metabolism, NADP reduction, oxygen detoxification, and sulfite reduction. By converting NO2 back to NO with F420H2, M. tuberculosis could decrease the effectiveness of antibacterial action of macrophages[3].

Molecular Weight







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