DGKα-IN-9
DGKα-IN-9 is a diacylglycerol kinase alpha (DGKα) inhibitor. DGKα-IN-9 demonstrates a tumor growth inhibition in MC38 or or CT26 mouse tumor model. DGKα-IN-9 can be used for the study of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2980406-85-5
- Formula: C26H23ClF3N3O4
- Molecular Weight:533.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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DGKα |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:MC38 tumor cells or CT26 tumor cells (in 0.1 mL DPBS) were subcutaneously implanted into the right flanks of mice for tumor development [1]
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Dosage:0.5, 3 mg/kg
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Administration:p.o., twice daily, combined with Anti-mPD-1 or Anti-mCTLA-4
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Result:Achieved tumor growth inhibition.
Chemical Information
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CAS No. 2980406-85-5
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Molecular Weight 533.93
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Formula C26H23ClF3N3O4
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SMILES
ClC1=CC2=C(N(C)C(N=C2N3C4=C(C(C#CC5(CC5)C(F)(F)F)=CC=C4)COCC3)=O)C=C1OCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)