Glucose-PEG2000-N3
Glucose-PEG2000-N3 (Glucose-PEG2000-Azide) is a conjugate composed of glucose, PEG chains, and an azide group (-N3). Glucose-PEG2000-N3 combines the targeted recognition ability of glucose with the azide group that can undergo click chemistry, making it suitable for applications such as constructing targeted drug delivery systems and nanoparticle modification.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
The structure of Glucose-PEG-N3 comprises three key components that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), achieving receptor-mediated active targeted delivery.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Azide group: Can undergo copper-catalyzed azido-azide cycloaddition (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven azido-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOCCN=[N+]=[N-])=O)O)O)CO.[n]
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Synonyms
Glucose-PEG2000-Azide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)