2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. DMBA-SIL-Mal-MMAE

DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked DMBA-SIL-Mal.

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DMBA-SIL-Mal-MMAE

DMBA-SIL-Mal-MMAE 화학구조

CAS No. : 2923885-49-6

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg   견적 받기  
200 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

DMBA-SIL-Mal-MMAE Related Antibodies

Top Publications Citing Use of Products

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents Dual payloads

  • Biological Activity

  • 순도&문서

  • References

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제품 설명

DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked DMBA-SIL-Mal[1].

분자량

1403.65

화학식

C72H106N8O20
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OC(C3=CC=C(C=C3)NC(OCC4=CC(OC)=CC(OC)=C4)=O)C(NCCOCCOCCOCCOCCN5C(C=CC5=O)=O)=O)=O)=O)=O)=O)OC)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

순도&문서
References
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DMBA-SIL-Mal-MMAE Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMBA-SIL-Mal-MMAE2923885-49-6Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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상품명:
DMBA-SIL-Mal-MMAE
Cat. No.:
HY-160702
수량:
MCE Japan Authorized Agent:

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