1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Dopamine D3 receptor ligand-2

Dopamine D3 receptor ligand-2 (compound 8) is a potent D3 receptor ligand with a Ki of 11.4 nM. Dopamine D3 receptor ligand-2 have high selectivity for D3 over D2 (Ki=1228 nM).

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Dopamine D3 receptor ligand-2 Chemical Structure

Dopamine D3 receptor ligand-2 Chemical Structure

CAS No. : 2882828-95-5

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Description

Dopamine D3 receptor ligand-2 (compound 8) is a potent D3 receptor ligand with a Ki of 11.4 nM. Dopamine D3 receptor ligand-2 have high selectivity for D3 over D2 (Ki=1228 nM)[1].

IC50 & Target[1]

D3 Receptor

11.4 nM (Ki)

D2 Receptor

1228 nM (Ki)

Molecular Weight

439.55

Formula

C27H29N5O

CAS No.
SMILES

N#CC1=CC(N2CCN(CC2)CCCCC(NC3=CC=C(C=C3)C4=NC=CC=C4)=O)=CC=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Dopamine D3 receptor ligand-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dopamine D3 receptor ligand-2
Cat. No.:
HY-115954
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