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  6. (E)-Methyl 3,4,5-trimethoxycinnamate

(E)-Methyl 3,4,5-trimethoxycinnamate is a bioactive natural phenylpropanoid. (E)-Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. (E)-Methyl 3,4,5-trimethoxycinnamate also has antiarrhythmic effect, leads to suppression of triggered activities in rabbit myocytes.

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(E)-Methyl 3,4,5-trimethoxycinnamate

(E)-Methyl 3,4,5-trimethoxycinnamate Chemical Structure

CAS No. : 20329-96-8

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(E)-Methyl 3,4,5-trimethoxycinnamate Related Antibodies

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Description

(E)-Methyl 3,4,5-trimethoxycinnamate is a bioactive natural phenylpropanoid. (E)-Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. (E)-Methyl 3,4,5-trimethoxycinnamate also has antiarrhythmic effect, leads to suppression of triggered activities in rabbit myocytes[1][2].

Molecular Weight

252.26

Formula

C13H16O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC)/C=C/C1=CC(OC)=C(OC)C(OC)=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (39.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9642 mL 19.8208 mL 39.6416 mL
5 mM 0.7928 mL 3.9642 mL 7.9283 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9642 mL 19.8208 mL 39.6416 mL 99.1041 mL
5 mM 0.7928 mL 3.9642 mL 7.9283 mL 19.8208 mL
10 mM 0.3964 mL 1.9821 mL 3.9642 mL 9.9104 mL
15 mM 0.2643 mL 1.3214 mL 2.6428 mL 6.6069 mL
20 mM 0.1982 mL 0.9910 mL 1.9821 mL 4.9552 mL
25 mM 0.1586 mL 0.7928 mL 1.5857 mL 3.9642 mL
30 mM 0.1321 mL 0.6607 mL 1.3214 mL 3.3035 mL
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(E)-Methyl 3,4,5-trimethoxycinnamate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-Methyl 3,4,5-trimethoxycinnamate20329-96-8OthersInhibitorinhibitorinhibit

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