1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Cell Cycle/DNA Damage
  2. EGFR CDK
  3. EGFR/CDK2-IN-1

EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research.

For research use only. We do not sell to patients.

EGFR/CDK2-IN-1 Chemical Structure

EGFR/CDK2-IN-1 Chemical Structure

CAS No. : 2841405-96-5

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Description

EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1].

IC50 & Target

EGFR, CDK-2[1].

In Vitro

EGFR/CDK2-IN-1 (0-20 μM; 48 h) shows excellent activity in both MCF7 and HepG2 with IC50 values of 4.1 and 3.5 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: MCF7, HepG2 cells
Concentration: 0-20 μM
Incubation Time: 48 h
Result: Exhibited good cytotoxic activity in breast and liver cancer cells.
Molecular Weight

387.65

Formula

C19H12BrClO2

CAS No.
SMILES

O=C(C1=CC=C(Br)C=C1)/C=C/C2=CC=C(C3=CC=CC=C3Cl)O2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Product Name:
EGFR/CDK2-IN-1
Cat. No.:
HY-151573
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