EGFR/VEGFR2-IN-6
EGFR/VEGFR2-IN-6 (Compound 3k) is a dual-functional inhibitor of EGFR and VEGFR2 with IC50s of 10.53 and 3.37 μM for EGFR and VEGFR2, respectively. EGFR/VEGFR2-IN-6 has significant anti-proliferation activity against breast cancer cells, and induces G0/G1 cell cycle arrest and cell apoptosis, especially early apoptosis. EGFR/VEGFR2-IN-6 can be used for cancers research.
For research use only. We do not sell to patients.
- Formula: C24H18F3N3O5
- Molecular Weight:485.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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VEGFR2 3.37 μM (IC50) |
EGFR 10.53 μM (IC50) |
Chemical Information
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Molecular Weight 485.41
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Formula C24H18F3N3O5
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SMILES
FC(C1=CC=C(N/N=C/C2=C(OC(C3=CC(OC)=CC(OC)=C3)=C4)C4=CC([N+]([O-])=O)=C2)C=C1)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/VEGFR2-IN-6 Related Classifications
HY-175635 Related Classifications
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