Benzomalvin C
Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/mL in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. It is isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E.
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- No. CAS: 157047-98-8
- Fòrmula: C24H17N3O3
- Peso molecular:395.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 157047-98-8
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Peso molecular 395.41
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Fòrmula C24H17N3O3
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SMILES
O=C1C2=C(N=C3N1C4=C(C(N([C@]35O[C@@H]5C6=CC=CC=C6)C)=O)C=CC=C4)C=CC=C2
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Structure Classification
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Initial Source
Aspergillus sp.
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Benzomalvin C Related Classifications
HY-116620 Related Classifications
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