Etamiphyllin camsylate
Etamiphyllin (Etamiphylline) camsylate is a respiratory and cardiac stimulant. Etamiphyllin camsylate relaxes bronchial and bronchiolar smooth muscle to open airways, and increases cardiac output without elevating heart rate. The level of Etamiphyllin camsylate decreases in mice with ulcerative colitis, and it is positively correlated with *Bifidobacterium* and *Faecalibacterium*. Etamiphyllin camsylate can be applied to research related to chronic obstructive pulmonary disease, respiratory failure and ulcerative colitis.
For research use only. We do not sell to patients.
- CAS No.: 19326-29-5
- Formula: C23H37N5O6S
- Molecular Weight:511.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Thoroughbred (male, ages 6 and 16, body weights 498 and 537 kg)[2]
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Dosage:2.8 mg/kg
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Administration:i.v.; single dose
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Result:Detected in plasma and urine samples, with a characteristic m/z 207 fragment ion from loss of N,N-diethylamine.
Detected the main metabolite, N-desethyletamiphylline (molecular weight 251), in plasma and urine up to 32 hours post-administration, with a protonated molecular ion ([M+H]+) at m/z 252.1455 and product ions at m/z 207.0879 and m/z 163.0979.
Detected two isomers of N1/N3-desmethyletamiphylline (molecular weight 265) as minor metabolites in plasma and urine, with [M+H]+ ions at m/z 266.1613 and m/z 266.1615, and common product ion m/z 193.0721/193.0723 from loss of N,N-diethylamine.
Detected N-desethyl-N-desmethyletamiphylline (molecular weight 238) as a minor metabolite in urine, with [M+H]+ ion at m/z 238.1300 and product ion m/z 193.0722 from loss of N-ethylamine.
Chemical Information
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CAS No. 19326-29-5
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Molecular Weight 511.63
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Formula C23H37N5O6S
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SMILES
CCN(CC)CCN1C2=C(N(C(N(C)C2=O)=O)C)N=C1.O=S(C[C@@]3(C4(C)C)C(C[C@@]4([H])CC3)=O)(O)=O
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Synonyms
Etamiphylline camsylate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Etamiphyllin camsylate Related Classifications
HY-105762A Related Classifications
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