Exatecan-mpGly-Asn-Asn-(βAla)
Based on 1 Customer Validation
Exatecan-mpGly-Asn-Asn-(βAla) (Compound 10b) is a conjugate of Exatecan (HY-13631) and a linker. Exatecan-mpGly-Asn-Asn-(βAla) can be used to synthesize ADCs, such as α-HER2_mpGlyAsnAsn(β-Ala)_Exatecan. Exatecan-mpGly-Asn-Asn-(βAla) can also be used in tumor research.
For research use only. We do not sell to patients.
- Purity: 96.74%
- CAS No.: 3076725-07-7
- Formula: C44H47FN10O13
- Molecular Weight:942.90
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 3076725-07-7
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Appearance Solid
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Molecular Weight 942.90
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Formula C44H47FN10O13
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Color Light yellow to yellow
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SMILES
O=C(C=CC1=O)N1CCC(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(NCCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (106.06 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0606 mL | 5.3028 mL | 10.6056 mL | 26.5139 mL |
| 5 mM | 0.2121 mL | 1.0606 mL | 2.1211 mL | 5.3028 mL | |
| 10 mM | 0.1061 mL | 0.5303 mL | 1.0606 mL | 2.6514 mL | |
| 15 mM | 0.0707 mL | 0.3535 mL | 0.7070 mL | 1.7676 mL | |
| 20 mM | 0.0530 mL | 0.2651 mL | 0.5303 mL | 1.3257 mL | |
| 25 mM | 0.0424 mL | 0.2121 mL | 0.4242 mL | 1.0606 mL | |
| 30 mM | 0.0354 mL | 0.1768 mL | 0.3535 mL | 0.8838 mL | |
| 40 mM | 0.0265 mL | 0.1326 mL | 0.2651 mL | 0.6628 mL | |
| 50 mM | 0.0212 mL | 0.1061 mL | 0.2121 mL | 0.5303 mL | |
| 60 mM | 0.0177 mL | 0.0884 mL | 0.1768 mL | 0.4419 mL | |
| 80 mM | 0.0133 mL | 0.0663 mL | 0.1326 mL | 0.3314 mL | |
| 100 mM | 0.0106 mL | 0.0530 mL | 0.1061 mL | 0.2651 mL |
Exatecan-mpGly-Asn-Asn-(βAla) Related Classifications
HY-176977 Related Classifications
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