2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. FC9402

FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation.

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FC9402

FC9402 Estructura química

No. CAS : 2452401-65-7

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

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Based on 2 publication(s) in Google Scholar

FC9402 Related Antibodies

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Descripciòn

FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation[1].

IC50 & Target

SQOR[1]
In Vitro

FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FC9402 Related Antibodies
Peso molecular

316.36

Fòrmula

C19H16N4O
No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

N#CC1=C(OC)N=C(C2=NC=CC=C2C)C=C1C3=CC=C(N)C=C3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (316.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1610 mL 15.8048 mL 31.6096 mL
5 mM 0.6322 mL 3.1610 mL 6.3219 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 98.19%

SDS (251 KB)

COA (250 KB) HNMR (299 KB) LCMS (94 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1610 mL 15.8048 mL 31.6096 mL 79.0239 mL
5 mM 0.6322 mL 3.1610 mL 6.3219 mL 15.8048 mL
10 mM 0.3161 mL 1.5805 mL 3.1610 mL 7.9024 mL
15 mM 0.2107 mL 1.0537 mL 2.1073 mL 5.2683 mL
20 mM 0.1580 mL 0.7902 mL 1.5805 mL 3.9512 mL
25 mM 0.1264 mL 0.6322 mL 1.2644 mL 3.1610 mL
30 mM 0.1054 mL 0.5268 mL 1.0537 mL 2.6341 mL
40 mM 0.0790 mL 0.3951 mL 0.7902 mL 1.9756 mL
50 mM 0.0632 mL 0.3161 mL 0.6322 mL 1.5805 mL
60 mM 0.0527 mL 0.2634 mL 0.5268 mL 1.3171 mL
80 mM 0.0395 mL 0.1976 mL 0.3951 mL 0.9878 mL
100 mM 0.0316 mL 0.1580 mL 0.3161 mL 0.7902 mL
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FC9402 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FC94022452401-65-7FC 9402FC-9402Mitochondrial MetabolismcardiomyocytehypertrophyventriclefibrosiscardiovascularInhibitorinhibitorinhibit

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Nombre del producto:
FC9402
Cat. No.:
HY-141552
Cantidad:
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SAFETY DATA SHEET (SDS)

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