2. PROTAC
  3. PROTAC Linkers
  4. Fmoc-amino-(PEG)n-acid

Fmoc-amino-(PEG)n-acid is a PEG-based PROTAC linker containing an Fmoc-protected amine and a terminal carboxylic acid and can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Fmoc-amino-(PEG)n-acid

Fmoc-amino-(PEG)n-acid Chemical Structure

CAS No. : 850312-72-0

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Fmoc-amino-(PEG)n-acid Related Antibodies

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Description

Fmoc-amino-(PEG)n-acid is a PEG-based PROTAC linker containing an Fmoc-protected amine and a terminal carboxylic acid and can be used in the synthesis of PROTACs.

In Vitro

The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-amino-(PEG)n-acid Related Antibodies
Formula

(C2H4O)nC20H21NO5
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC(CCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
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Fmoc-amino-(PEG)n-acid Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-amino-(PEG)n-acid850312-72-0PROTAC LinkersInhibitorinhibitorinhibit

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Fmoc-amino-(PEG)n-acid
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