Fmoc-amino-(PEG)n-acid
Fmoc-amino-(PEG)n-acid is a PEG-based PROTAC linker containing an Fmoc-protected amine and a terminal carboxylic acid and can be used in the synthesis of PROTACs.
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- No. CAS: 850312-72-0
- Fòrmula: (C2H4O)nC20H21NO5
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Chemical Information
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Actividad biológica
Descripciòn
In Vitro
The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 850312-72-0
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Appearance Liquid
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Fòrmula (C2H4O)nC20H21NO5
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Color Colorless to light yellow
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SMILES
OC(CCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O.[n]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fmoc-amino-(PEG)n-acid Related Classifications
HY-W019797 Related Classifications
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