2. Antibody-drug Conjugate/ADC Related Cytoskeleton Cell Cycle/DNA Damage
  3. Microtubule/Tubulin ADC Payload
  4. Fmoc-MMAF-OMe

Fmoc-MMAF-OMe is an anticancer agent and tubulin polymerization inhibitor with an Fmoc protecting group. The active ingredient of Fmoc-MMAF-OMe, MMAF (HY-15579), is the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs).

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Fmoc-MMAF-OMe

Fmoc-MMAF-OMe 構造式

CAS 番号 : 863971-38-4

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 96 在庫あり
Solution
10 mM * 1 mL in DMSO USD 96 在庫あり
Solid
5 mg $45 在庫あり
10 mg $60 在庫あり
25 mg $100 在庫あり
50 mg $140 在庫あり
100 mg $200 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Fmoc-MMAF-OMe 関連抗体

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製品説明

Fmoc-MMAF-OMe is an anticancer agent and tubulin polymerization inhibitor with an Fmoc protecting group. The active ingredient of Fmoc-MMAF-OMe, MMAF (HY-15579), is the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs)[1].

分子量

968.23

分子式

C55H77N5O10
CAS 番号
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(OC)=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C)=O)=O)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 200 mg/mL (206.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0328 mL 5.1641 mL 10.3281 mL
5 mM 0.2066 mL 1.0328 mL 2.0656 mL
10 mM 0.1033 mL 0.5164 mL 1.0328 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0328 mL 5.1641 mL 10.3281 mL 25.8203 mL
5 mM 0.2066 mL 1.0328 mL 2.0656 mL 5.1641 mL
10 mM 0.1033 mL 0.5164 mL 1.0328 mL 2.5820 mL
15 mM 0.0689 mL 0.3443 mL 0.6885 mL 1.7214 mL
20 mM 0.0516 mL 0.2582 mL 0.5164 mL 1.2910 mL
25 mM 0.0413 mL 0.2066 mL 0.4131 mL 1.0328 mL
30 mM 0.0344 mL 0.1721 mL 0.3443 mL 0.8607 mL
40 mM 0.0258 mL 0.1291 mL 0.2582 mL 0.6455 mL
50 mM 0.0207 mL 0.1033 mL 0.2066 mL 0.5164 mL
60 mM 0.0172 mL 0.0861 mL 0.1721 mL 0.4303 mL
80 mM 0.0129 mL 0.0646 mL 0.1291 mL 0.3228 mL
100 mM 0.0103 mL 0.0516 mL 0.1033 mL 0.2582 mL
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Fmoc-MMAF-OMe Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-MMAF-OMe863971-38-4Microtubule/TubulinADC PayloadADC CytotoxinInhibitorinhibitorinhibit

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製品名:
Fmoc-MMAF-OMe
製品番号:
HY-79255
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