Olanzapine-d15
Olanzapine-d15 (LY170053-d15) is the deuterium labeled Olanzapine (HY-14541). Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki = 7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki = 11 to 31 nM), muscarinic M1-5 (Ki = 1.9-25 nM), and adrenergic α1 receptor (Ki = 19 nM). Olanzapine is an atypical antipsychotic.
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- CAS No.: 1252611-25-8
- Formule: C17H5D15N4S
- Masse moléculaire:327.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1252611-25-8
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Unlabeled Cas 132539-06-1
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Masse moléculaire 327.52
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Formule C17H5D15N4S
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SMILES
CC1=CC2=C(S1)NC3=C([2H])C([2H])=C([2H])C([2H])=C3N=C2N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C([2H])([2H])[2H]
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Synonyms
LY170053-d15
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)