Aspochalasin D
Based on 1 Customer Validation
Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that is initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml.2 Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s=0.49 and 1.9 μg/mL, respectively).
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- Pureza : 98.24%
- No. CAS: 71968-02-0
- Fòrmula: C24H35NO4
- Peso molecular:401.54
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>20 μM
Compound: 3
|
Cytotoxicity against human A2780 cells by MTT assay
Cytotoxicity against human A2780 cells by MTT assay
|
[PMID: 39258410] |
| HeLa | IC50 |
>20 μM
Compound: 3
|
Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
|
[PMID: 39258410] |
| HepG2 | IC50 |
>20 μM
Compound: 3
|
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
|
[PMID: 39258410] |
| SK-OV-3 | IC50 |
>20 μM
Compound: 3
|
Cytotoxicity against human SK-OV-3 cells by MTT assay
Cytotoxicity against human SK-OV-3 cells by MTT assay
|
[PMID: 39258410] |
Chemical Information
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No. CAS 71968-02-0
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Appearance Solid
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Peso molecular 401.54
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Fòrmula C24H35NO4
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Color White to off-white
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SMILES
O=C1N[C@@H](CC(C)C)[C@]2([H])[C@H](C)C(C)=C[C@@](/C=C(C)/CC[C@@H](O)[C@@H](O)/C=C/3)([H])[C@]12C3=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)