AT-1015
AT-1015 is a selective and orally active 5-HT2A serotonin receptor antagonist. AT-1015 exhibits antithrombotic effect. AT-1015 prolongs the time needed to occlusion of the artery with thrombus. AT-1015 impairs platelet aggregation and vasoconstriction.
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- No. CAS: 190508-48-6
- Fòrmula: C29H36ClN3O3
- Peso molecular:510.07
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Chemical Information
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No. CAS 190508-48-6
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Peso molecular 510.07
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Fòrmula C29H36ClN3O3
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SMILES
O=C(C1CCN(C=O)CC1)NCCN2CC/C(CC2)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35.O.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Hiatt, W. R., et al., (2004). Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy. Vascular medicine (London, England), 9(1), 18-25. [Content Brief]
[2]. Kihara, H., et al., (2001). Antithrombotic activity of AT-1015, a potent 5-HT(2A) receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time. European journal of pharmacology, 433(2-3), 157-162. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AT-1015 Related Classifications
HY-165594A Related Classifications
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