Ucp3 - uncoupling protein 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25708

Summary

Predicted to enable Oxidative Phosphorylation uncoupler activity. Involved in several processes, including response to activity; response to insulin; and response to superoxide. Located in mitochondrion. Used to study type 2 diabetes mellitus. Biomarker of congestive heart failure; hypertension; hyperthyroidism; hypothyroidism; and prediabetes syndrome. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Ucp3 Products (1)

mRNA Protein Name
NM_013167.2 NP_037299.1 mitochondrial uncoupling protein 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Referencias Source
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
17478558 RGD
involved in response to activity IEP
IEP: Inferred from expression pattern
18977294 RGD
involved in response to fenofibrate IEP
IEP: Inferred from expression pattern
11934685 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
18591261 RGD
involved in response to hypoxia IDA
IDA: Inferred from direct assay
15292030 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
19082433 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
10868941 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
16962595 RGD
involved in response to steroid hormone IEP
IEP: Inferred from expression pattern
12659879 RGD
involved in response to superoxide IDA
IDA: Inferred from direct assay
11780125 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial uncoupling protein 3

  • UCP 3

  • Uncoupling protein 3, mitochondrial

  • solute carrier family 25 member 9

  • uncoupling protein 3 (mitochondrial, proton carrier)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto Efecto
Pureza Phase
HY-117549 Ibrolipim Activator 99.48% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-11032 SM-350300 / Unkown
HY-RS15412 UCP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20349 Ucp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26858 Ucp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucp3 NCBI NCBI:7352