country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-10840

Copy Link Print Information

PPARδ agonist 14

PPARδ agonist 14 (Cpd 33) is a selective PPARδ agonist with an EC₅₀ of 3 nM for PPARδ. PPARδ agonist 14 shows no cross-activity against PPARα and PPARγ. PPARδ agonist 14 can be used for research on PPARδ-related metabolic diseases.

For research use only. We do not sell to patients.

CAS No.: 518336-59-9
Formula: C₂₄H₂₈Cl₂N₂O₄
Molecular Weight:479.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PPARδ agonist 14 Chemical Structure

CAS No.: 518336-59-9

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

PPARδ

3 nM (EC₅₀)

All PPAR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	0.003 μM Compound: 2	Agonist activity at Gal4-fused human PPARdelta DNA binding domain expressed in HEK293 cells by luciferase reporter gene assay Agonist activity at Gal4-fused human PPARdelta DNA binding domain expressed in HEK293 cells by luciferase reporter gene assay	[PMID: 21094606]

Chemical Information

CAS No. 518336-59-9
Molecular Weight 479.40
Formula C₂₄H₂₈Cl₂N₂O₄
SMILES

O=C(O)COC1=CC=C(C=C1C)CN(CC(=O)NC2=CC=C(Cl)C=C2Cl)C3CCCCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Epple R, et al. Novel bisaryl substituted thiazoles and oxazoles as highly potent and selective peroxisome proliferator-activated receptor delta agonists. Journal of medicinal chemistry. 2010 Jan 14;53(1):77-105.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote