Glucose-PEG1000-OH
Glucose-PEG1000-OH is a conjugate composed of glucose, PEG chains, and hydroxyl groups (-OH). Glucose-PEG1000-OH combines the targeted recognition capability of glucose with the modification flexibility of hydroxyl groups, enabling applications such as targeted drug delivery systems and nanoparticle modification.
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
The structure of Glucose-PEG-OH comprises three key components that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), achieving receptor-mediated active targeted delivery.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Hydroxyl group (-OH): An active group that can serve as a starting point for further chemical reactions, used for coupling drug molecules, linking other targeted ligands, or for material surface modification.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOCCO)=O)O)O)CO.[n]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)