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Referencia número: HY-183161A

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Glucose-PEG2000-N3

(Synonyms: Glucose-PEG2000-Azide)

Glucose-PEG2000-N3 (Glucose-PEG2000-Azide) is a conjugate composed of glucose, PEG chains, and an azide group (-N3). Glucose-PEG2000-N3 combines the targeted recognition ability of glucose with the azide group that can undergo click chemistry, making it suitable for applications such as constructing targeted drug delivery systems and nanoparticle modification.

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Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Glucose-PEG2000-N3 Chemical Structure

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Actividad biológica

Descripciòn

In Vitro

The structure of Glucose-PEG-N3 comprises three key components that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), achieving receptor-mediated active targeted delivery.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Azide group: Can undergo copper-catalyzed azido-azide cycloaddition (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven azido-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOCCN=[N+]=[N-])=O)O)O)CO.[n]
Synonyms

Glucose-PEG2000-Azide
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.