KRN383 analog
KRN383 analog is an analog of KRN383. KRN383 is an orally active Flt3 inhibitor that inhibits the autophosphorylation of Flt3 bearing internal tandem duplications (ITDs) and the Asp835Tyr (D835Y) point mutation with IC50 values of < or =5.9 and 43 nM, respectively. KRN383 also inhibits the proliferation of the ITD-positive cell lines with IC50 values of < or =2.9 nM. KRN383 can be used for the research of acute myeloid leukemia.
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- No. CAS: 919767-02-5
- Fòrmula: C17H17N3O4
- Peso molecular:327.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 919767-02-5
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Peso molecular 327.33
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Fòrmula C17H17N3O4
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SMILES
O=C(NC1=CCC(C=C1)OC2=CC=NC3=CC(O)=C(C=C23)OC)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRN383 analog Related Classifications
HY-123201 Related Classifications
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