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United States

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Referencia número: HY-156471

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RET-IN-26

RET-IN-26 (compound D5) is RET kinase inhibitor, with the IC₅₀ of 0.33 μM.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₃H₂₇N₅O₂
Peso molecular:405.49

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

RET-IN-26 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

RET-IN-26 (compound D5) is RET kinase inhibitor, with the IC₅₀ of 0.33 μM^[1].

IC₅₀ & Target

0.33 μM^[1]

Chemical Information

Peso molecular 405.49
Fòrmula C₂₃H₂₇N₅O₂
SMILES

O=C1NC2=CC(C#N)=CC=C2/C1=C/C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Zhenzhu Li, et al. Design and synthesis of indol-2-one derivatives as potential RET inhibitors. Bioorganic & Medicinal Chemistry Letters Available online 29 October 2023, 129538

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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