HNRNPA0 - heterogeneous nuclear ribonucleoprotein A0 Gene
Also Known as HNRPA0
Species: Homo sapiens
About HNRNPA0
This gene has 1 transcript (splice variant), 139 orthologues and 36 paralogues.
Summary
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and Other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008]
HNRNPA0 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_006805.4 | NP_006796.1 | heterogeneous nuclear ribonucleoprotein A0 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables mRNA 3'-UTR AU-rich region binding |
IDA
IDA: Inferred from direct assay
|
20932473 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
30021884 | GOA |
| enables protein kinase binding |
IPI
IPI: Inferred from physical interaction
|
20932473 | GOA |
HNRNPA0 Protein Structure
(9 - 78)
RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (100 - 168)
- 0
- 100
- 200
- 305 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
heterogeneous nuclear ribonucleoprotein A0 |
|
HNRNPA0 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P86903 | HNRNPA0 Antibody (YA6596) | WB, ICC/IF, IHC-P, FC | Human, Mouse, Rat, Monkey |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | HNRNPA0 | VGNC | VGNC:52238 |
| Mus musculus | HNRNPA0 | MGD | MGI:1924384 |
| Canis familiaris | HNRNPA0 | VGNC | VGNC:51722 |
| Rattus norvegicus | HNRNPA0 | RGD | RGD:1563684 |
| Others | HNRNPA0 | NCBI |