Psd - pleckstrin and Sec7 domain containing Gene

Also Known as EFA6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171381

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in neuron differentiation. Is integral component of membrane. Orthologous to human PSD (pleckstrin and Sec7 domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Psd Products (1)

mRNA Protein Name
NM_134370.2 NP_599197.2 PH and SEC7 domain-containing protein 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in maintenance of postsynaptic density structure IDA
IDA: Inferred from direct assay
16672654 RGD
involved in maintenance of postsynaptic density structure IMP
IMP: Inferred from mutant phenotype
16672654 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
11834294 RGD
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
16672654 RGD
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
16672654 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
16672654 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
16672654 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PH and SEC7 domain-containing protein 1

  • exchange factor for ADP-ribosylation factor guanine nucleotide factor 6

  • exchange factor for ARF6 A

  • pleckstrin homology and SEC7 domain-containing protein 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-P0117 Tat-NR2B9c Inhibitor 99.89% Phase 3
HY-135741 NYX-2925 Modulator 98.98% Phase 2
HY-123566 PSD-506 Antagonist / Phase 2
HY-P11263 AVLX-144 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (33)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W009118 Fmoc-5-Ava-OH 99.49% Unkown
HY-164288 TDI-6570 Inhibitor 99.64% Unkown
HY-100456 ZL006 Inhibitor 99.23% Unkown
HY-117772 FSC231 Inhibitor 99.51% Unkown
HY-146885S 16:0-18:1 PS-d31 sodium 99.60% Unkown
HY-100457 IC87201 Inhibitor 97.24% Unkown
HY-P0117A Tat-NR2B9c TFA Inhibitor 99.66% Unkown
HY-P1195 PDZ1 Domain inhibitor peptide 99.21% Unkown
HY-P2307 Tat-NR2Baa 96.89% Unkown
HY-145539SA 1,2-Dipalmitoyl-sn-glycero-3-PS-d62 ammonium 95.0% Unkown
HY-100458 SCR-4026 Inhibitor / Unkown
HY-145539S 1,2-Dipalmitoyl-sn-glycero-3-PS-d62 sodium salt 99.0% Unkown
HY-155355 LY836 Inhibitor / Unkown
HY-167592S 17:0-20:3 PS-d5 99% Unkown
HY-175824 PSD-95/nNOS PPI-IN-1 Inhibitor / Unkown
HY-176866 Rodin-A Inhibitor / Unkown
HY-176867 Rodin-B Inhibitor / Unkown
HY-178737S 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium / Unkown
HY-178754S 12-Dipalmitoyl-sn-glycero-3-PS-d3 ammonium / Unkown
HY-184078 8-F-2-(Me-Pip-Me)-Tryptanthrin Inhibitor / Unkown
HY-184108 ZL006-05 / Unkown
HY-P10212 AVLX-125 Inhibitor / Unkown
HY-P1195A PDZ1 Domain inhibitor peptide TFA / Unkown
HY-P2307A Tat-NR2Baa TFA / Unkown
HY-RS10573 PISD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11272 PSD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11273 PSD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11274 PSD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11275 PSD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-143675S 1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS-d9 / Unkown
HY-P10401 TAT-GluR6-9c Antagonist / Unkown
HY-RS18221 Psd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24698 Psd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psd NCBI NCBI:5662