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Cat. No.: HY-P10212

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AVLX-125

(Synonyms: UCCB01-125)

AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with K_d value of 10 nM. AVLX-125 can be used in the study of inflammatory pain.

For research use only. We do not sell to patients.

CAS No.: 1786434-31-8
Formula: C₆₂H₁₀₄N₁₀O₂₉
Molecular Weight:1453.54

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AVLX-125 Chemical Structure

CAS No.: 1786434-31-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with K_d value of 10 nM. AVLX-125 can be used in the study of inflammatory pain^[1]^[2].

All iGluR Isoforms :

Chemical Information

CAS No. 1786434-31-8
Molecular Weight 1453.54
Formula C₆₂H₁₀₄N₁₀O₂₉
Synonyms

UCCB01-125
Sequence

Val-Asp-Thr-Glu-Ile-Ile-Glu-Thr-Asp-Val Covalent bridge:Ile5-Ile6
Sequence Shortening

VDTEIIETDV Covalent bridge:Ile5-Ile6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Haugaard-Kedström L M, et al. Targeting PSD-95 as a novel approach in the treatment of stroke. Neuroprotective Therapy for Stroke and Ischemic Disease, 2017: 157-184.

[2]. Andreasen JT, et al. UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: comparison with the NMDA receptor antagonist MK-801. Neuropharmacology. 2013 Apr;67:193-200. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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AVLX-125

All iGluR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

AVLX-125 Related Classifications

HY-P10212 Related Classifications