1786434-31-8
1786434-31-8
Chemical Structure
AVLX-125
Synonym(s): UCCB01-125
- CAS No.: 1786434-31-8
- Formula:C62H104N10O29
- Molecular Weight:1453.54
InChIKey: YKWWWHGLWROAKO-KWRPVYMMSA-N
SMILES: CC(C)[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC(CCOCCOCCOCCOCCOCCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with Kd value of 10 nM. AVLX-125 can be used in the study of inflammatory pain[1][2].
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AVLX-125 | AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with Kd value of 10 nM. AVLX-125 can be used in the study of inflammatory pain. | |||||||||||||||||||||
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References
- [1]. Haugaard-Kedström L M, et al. Targeting PSD-95 as a novel approach in the treatment of stroke. Neuroprotective Therapy for Stroke and Ischemic Disease, 2017: 157-184.
- [2]. Andreasen JT, et al. UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: comparison with the NMDA receptor antagonist MK-801. Neuropharmacology. 2013 Apr;67:193-200. [Content Brief]
