Npy2r - neuropeptide Y receptor Y2 Gene

Mus musculus

Also known as NPY2-R

Gene ID: 18167 | Gene type: protein coding

About Npy2r

Chromosome 3: 82,445,690-82,455,391 reverse strand.GRCm39:CM000996.3

This gene has 4 transcripts (splice variants), 248 orthologues, 55 paralogues and is associated with 40 phenotypes. Biased expression in adrenal adult (RPKM 1.5), genital fat pad adult (RPKM 1.1) and 11 other tissues.

Summary

Enables peptide YY receptor activity. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in non-motile cilium. Is expressed in central nervous system; dorsal root ganglion; eye; and metanephros. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (Neuropeptide Y Receptor Y2). [provided by Alliance of Genome Resources, Apr 2022]

Npy2r Products(5)

mRNA	Protein	Name
NM_001410444.1	NP_001397373.1	neuropeptide Y receptor type 2 isoform 1
NM_001410445.1	NP_001397374.1	neuropeptide Y receptor type 2 isoform 1
NM_008731.4	NP_032757.2	neuropeptide Y receptor type 2 isoform 1
NM_001205099.2	NP_001192028.1	neuropeptide Y receptor type 2 isoform 2
NM_001410443.1	NP_001397372.1	neuropeptide Y receptor type 2 isoform 1

Npy2r Protein Structure

7tmA_NPY2R

0
100
200
300
381 a.a.

Protein Preferred Names

Protein Names

neuropeptide Y receptor type 2

NPY-Y2 receptor

Y2 receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-101986A	BIIE-0246 hydrochloride	Antagonist	≥99.0%	Unkown
HY-RS09514	NPY2R Human Pre-designed siRNA Set A		/	Unkown
HY-RS09515	Npy2r Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS09516	NPY2R Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Npy2r	NCBI	NCBI:4887

Name
Email *

	Sorry, but the email address you supplied was invalid.