Scgb1a1 - secretoglobin, family 1A, member 1 Gene

Also Known as UG; UGB; Utg; CC10; CC16; CCSP; PCB-BP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22287

Summary

Predicted to enable polychlorinated biphenyl binding activity. Acts upstream of or within several processes, including negative regulation of T cell proliferation; negative regulation of cytokine production; and regulation of RNA metabolic process. Located in cytoplasm. Is expressed in heart and respiratory system. Used to study IgA glomerulonephritis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; asthma; and glomerulonephritis. Orthologous to human SCGB1A1 (secretoglobin family 1A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Scgb1a1 Products (1)

mRNA Protein Name
NM_011681.2 NP_035811.1 uteroglobin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of T cell proliferation IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of interleukin-13 production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of interleukin-13 production IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of interleukin-4 production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of interleukin-5 production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of interleukin-5 production IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of or within negative regulation of T cell proliferation IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within negative regulation of interleukin-13 production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within negative regulation of interleukin-13 production IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of or within negative regulation of interleukin-4 production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within negative regulation of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of or within negative regulation of interleukin-5 production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within negative regulation of interleukin-5 production IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
15356574 MGI
acts upstream of or within negative regulation of type II interferon production IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within regulation of inflammatory response IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of or within regulation of mRNA stability IDA
IDA: Inferred from direct assay
15356574 MGI
acts upstream of type II interferon production IDA
IDA: Inferred from direct assay
15356574 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8813084 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
11724907 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uteroglobin

  • Blastokinin

  • CCPBP

  • PCB-binding protein

  • club cell 17 kDa protein

  • club cell phospholipid-binding protein

  • club cell secretory protein

  • club cells 10 kDa secretory protein

Recombinant Scgb1a1 Proteins

Cat. No. Product Name Accession Purity
HY-P71419 Uteroglobin/SCGB1A1 Protein, Mouse (HEK293, His) Q06318 (D22-F96) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P71936A Uteroglobin/SCGB1A1 Protein, Mouse (His) Q06318 (D22-96F) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12504 SCGB1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18577 Scgb1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25061 Scgb1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scgb1a1 NCBI NCBI:7356