Pdgfa - platelet derived growth factor subunit A Gene

Also Known as PDGFACP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25266

Summary

Predicted to enable several functions, including platelet-derived growth factor binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in several processes, including male gonad development; response to estradiol; and response to retinoic acid. Predicted to be located in cell surface and microvillus. Predicted to be active in extracellular space. Biomarker of chronic ulcer of skin; oligohydramnios; pancreatitis; pulmonary hypertension; and renovascular hypertension. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Pdgfa Products (1)

mRNA Protein Name
NM_012801.2 NP_036933.2 platelet-derived growth factor subunit A precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: Inferred from expression pattern
16039137 RGD
involved in inner ear development IEP
IEP: Inferred from expression pattern
15267171 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
11870082 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15267171 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
14724432 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
8447423 RGD
involved in response to retinoic acid IEP
IEP: Inferred from expression pattern
15315332 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16414398 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-derived growth factor subunit A

  • PDGF subunit A

  • PDGF-1

  • Platelet-derived growth factor A chain

  • platelet derived growth factor, alpha

  • platelet-derived growth factor alpha polypeptide

Recombinant Pdgfa Proteins

Cat. No. Product Name Accession Purity
HY-P73720 PDGF-AA Protein, Rat (P.pastoris, His) P28576-1 (R86-K204) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D0889 Glycylglycine 99.90% Unkown
HY-D0889R Glycylglycine (Standard) 99.91% Unkown
HY-RS10250 PDGFA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174553 Human PDGFA mRNA / Unkown
HY-RS17304 Pdgfa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23759 Pdgfa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W040074 Glycylglycine hydrochloride hydrate / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdgfa NCBI NCBI:5154