Mbnl1 - muscleblind-like splicing regulator 1 Gene

Also Known as Mbnl

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 282635

Summary

Enables regulatory region RNA binding activity. Predicted to be involved in RNA splicing; myoblast differentiation; and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; mRNA splicing, via spliceosome; and skeletal muscle tissue development. Located in nucleus. Orthologous to human MBNL1 (muscleblind like splicing regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Mbnl1 Products (2)

mRNA Protein Name
NM_001191566.2 NP_001178495.1 muscleblind-like protein 1 isoform 1
NM_001412543.1 NP_001399472.1 muscleblind-like protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables regulatory region RNA binding IDA
IDA: Inferred from direct assay
23511971 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
31283468 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

muscleblind-like protein 1

  • muscleblind-like 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0230 Phenylbutazone Inhibitor 99.69% Unkown

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B0230S Phenylbutazone(diphenyl-d10) Inhibitor 99.90% Unkown
HY-B0230S2 Phenylbutazone-13C12 Inhibitor 99.90% Unkown
HY-122970 1,2-Dihydrotanshinone 99.75% Unkown
HY-B0230S1 Phenylbutazone-d9 Inhibitor / Unkown
HY-RS08190 MBNL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174226 RNA binder 2 Ligand / Unkown
HY-RS17836 Mbnl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24304 Mbnl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbnl1 NCBI NCBI:4154