CLEC9A - C-type lectin domain containing 9A Gene

Also Known as CD370; DNGR1; DNGR-1; UNQ9341

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 283420

About CLEC9A

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,030,682-10,066,031 (from NCBI)

This gene has 3 transcripts (splice variants), 213 orthologues and 23 paralogues. Broad expression in lymph node (RPKM 3.7), spleen (RPKM 2.7) and 16 other tissues.

Summary

CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]

CLEC9A Products (1)

mRNA Protein Name
NM_207345.4 NP_997228.1 C-type lectin domain family 9 member A

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cytokine production IDA
IDA: Inferred from direct assay
18408006 GOA
involved in receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
18408006 GOA
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
18408006 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLEC9A Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (134 - 234)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

C-type lectin domain family 9 member A

  • HEEE9341

Recombinant CLEC9A Proteins

Cat. No. Product Name Accession Purity
HY-P77904 CLEC9A Protein, Human (HEK293, Fc) Q6UXN8 (K57-V241) ≥ 95%, as determined by Bis-Tris PAGE.

CLEC9A Antibodies

Cat. No. Product Name Application Reactivity
HY-P84645 CD370 Antibody (YA4342) ICC/IF, FC, ELISA Human
HY-P84645A CD370 Antibody (YA4342)(PBS only) ICC/IF, FC, ELISA Human

Related Diseases

Diseases Alias
Transvestism

  • Dual-Role Transvestism

  • Fetishistic Transvestism

  • Cross Dresser

  • Transvestic Fetishism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02801 CLEC9A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20145 Clec9a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26649 Clec9a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990258 Anti-Mouse CLEC9A/CD370 Antibody (7H11) Inhibitor 95% Unkown
HY-P991818 Anti-Mouse CD370 Antibody (1F6) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CLEC9A VGNC VGNC:58367
Macaca mulatta CLEC9A VGNC VGNC:71358
Felis catus CLEC9A VGNC VGNC:60956
Rattus norvegicus CLEC9A RGD RGD:1562513
Mus musculus CLEC9A MGD MGI:2444608
Others CLEC9A NCBI