Tsg101 - tumor susceptibility 101 Gene

Also Known as Rw

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292925

Summary

Enables nuclear receptor coactivator activity. Involved in endosome to lysosome transport and protein monoubiquitination. Located in endosome membrane and nucleus. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate Cancer. Orthologous to human TSG101 (tumor susceptibility 101). [provided by Alliance of Genome Resources, Apr 2022]

Tsg101 Products (1)

mRNA Protein Name
NM_181628.2 NP_853659.2 tumor susceptibility gene 101 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear receptor coactivator activity IDA
IDA: Inferred from direct assay
14761944 RGD
Biological Process GO Annotation Evidence References Source
involved in endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
19808888 RGD
involved in protein monoubiquitination IDA
IDA: Inferred from direct assay
14761944 RGD
Cellular Component GO Annotation Evidence References Source
located in endosome membrane IDA
IDA: Inferred from direct assay
11134028 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor susceptibility gene 101 protein

  • ESCRT-I complex subunit TSG101

  • Tumor supressor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-17421 Tenatoprazole Inhibitor 99.79% Unkown
HY-RS15142 TSG101 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19082 Tsg101 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P10845 KRL74 Inhibitor / Unkown
HY-RS25573 Tsg101 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991414 FGI-1011A6 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tsg101 NCBI NCBI:7251