Npsr1 - neuropeptide S receptor 1 Gene

Also Known as RGD1564154

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 300458

Summary

Predicted to enable neuropeptide receptor activity. Involved in several processes, including negative regulation of defecation; positive regulation of ERK1 and ERK2 cascade; and righting reflex. Predicted to be active in cytoplasm. Predicted to be integral component of plasma membrane. Biomarker of morphine dependence. Human ortholog(s) of this gene implicated in asthma; inflammatory bowel disease; newborn respiratory distress syndrome; and rheumatoid arthritis. Orthologous to human NPSR1 (Neuropeptide S Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Npsr1 Products (1)

mRNA Protein Name
NM_001106808.1 NP_001100278.1 neuropeptide S receptor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in eating behavior IMP
IMP: Inferred from mutant phenotype
20971145 RGD
involved in negative regulation of defecation IMP
IMP: Inferred from mutant phenotype
21708257 RGD
involved in negative regulation of eating behavior IMP
IMP: Inferred from mutant phenotype
19821837 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
23761908 RGD
involved in righting reflex IMP
IMP: Inferred from mutant phenotype
21288975 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuropeptide S receptor

  • G-protein coupled receptor 154

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-186036 R06039-641 Agonist 98.76% Unkown
HY-175813 NPSR1 antagonist-1 / Unkown
HY-186032 R06039-693 Agonist / Unkown
HY-186033 R06039-696 Agonist / Unkown
HY-P12119 RTI-263 Agonist / Unkown
HY-RS09503 NPSR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180875 NPSR1 modulator-1 / Unkown
HY-RS21667 Npsr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28185 Npsr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Npsr1 NCBI NCBI:387129