2. Gene
  3. LILRA5 - leukocyte immunoglobulin like receptor A5 Gene

LILRA5 - leukocyte immunoglobulin like receptor A5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7

Gene ID: 353514 | Gene type: protein coding

About LILRA5

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,307,070-54,313,166 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 295 orthologues and 25 paralogues. Biased expression in appendix (RPKM 29.5), bone marrow (RPKM 22.9) and 4 other tissues.

Summary

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

LILRA5 Products(4)

mRNA Protein Name
NM_021250.4 NP_067073.1 leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1 precursor
NM_181879.3 NP_870994.1 leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 3
NM_181985.4 NP_871714.1 leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 2
NM_181986.3 NP_871715.1 leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 4

LILRA5 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (48 - 135)

Ig_3

Ig_3: Immunoglobulin domain (141 - 217)

  • 0
  • 100
  • 200
  • 265 a.a.
Protein Preferred Names Protein Names

leukocyte immunoglobulin-like receptor subfamily A member 5

CD85 antigen-like family member F

Recombinant LILRA5 Proteins

Cat. No. Product Name Accession Purity
HY-P72394 LILRA5/CD85f Protein, Human (Biotinylated, HEK293, His-Avi) A6NI73 (G42-R268) ≥95%
HY-P72521 LILRA5/CD85f Protein, Human (HEK293, His) A6NI73 (G42-R268) ≥95%
HY-P75908 LILRA5/CD85f Protein, Human (Biotinylated, HEK 293, His-Avi) A6NI73 (M1-R268) ≥95%
HY-P75909 LILRA5/CD85f Protein, Human (Biotinylated, HEK293, His) A6NI73 (G42-R268) ≥95%
HY-P75910 LILRA5/CD85f Protein, Human (HEK293, Fc) A6NI73 (G42-R268) ≥95%
HY-P75911 LILRA5/CD85f Protein, Human (268a.a, HEK293, His) A6NI73 (M1-R268) ≥95%
HY-P78481 LILRA5/CD85f Protein, Human (HEK293, His-Avi) A6NI73 (G42-R268) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07649 LILRA5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LILRA5 RGD RGD:1582781
Mus musculus LILRA5 MGD MGI:3647196
Macaca mulatta LILRA5 VGNC VGNC:82174
Others LILRA5 NCBI