Gcdh - glutaryl-CoA dehydrogenase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364975

Summary

Enables fatty-acyl-CoA binding activity; flavin adenine dinucleotide binding activity; and glutaryl-CoA dehydrogenase activity. Involved in fatty acid oxidation and fatty-acyl-CoA biosynthetic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in glutaric acidemia I. Orthologous to human GCDH (glutaryl-CoA dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Gcdh Products (1)

mRNA Protein Name
NM_001108896.1 NP_001102366.1 glutaryl-CoA dehydrogenase, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fatty-acyl-CoA binding IDA
IDA: Inferred from direct assay
2899130 RGD
enables flavin adenine dinucleotide binding IDA
IDA: Inferred from direct assay
6895440 RGD
enables glutaryl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
2899130 RGD
Biological Process GO Annotation Evidence References Source
involved in acyl-CoA metabolic process IDA
IDA: Inferred from direct assay
6895440 RGD
involved in fatty acid oxidation IDA
IDA: Inferred from direct assay
2899130 RGD
involved in fatty-acyl-CoA biosynthetic process IDA
IDA: Inferred from direct assay
6895440 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutaryl-CoA dehydrogenase, mitochondrial

  • glutaryl-Coenzyme A dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05321 GCDH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-CE02028 Glutaconyl-CoA / Unkown
HY-RS19135 Gcdh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25625 Gcdh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gcdh NCBI NCBI:2639