NTRK2 - neurotrophic receptor tyrosine kinase 2 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
About NTRK2
This gene has 4 transcripts (splice variants), 288 orthologues and 54 paralogues.
NTRK2 Products (8)
| mRNA | Protein | Name |
|---|---|---|
| XM_038655058.1 | XP_038510986.1 | BDNF/NT-3 growth factors receptor isoform X5 |
| XM_038655060.1 | XP_038510988.1 | BDNF/NT-3 growth factors receptor isoform X7 |
| XM_038655055.1 | XP_038510983.1 | BDNF/NT-3 growth factors receptor isoform X2 |
| XM_038655059.1 | XP_038510987.1 | BDNF/NT-3 growth factors receptor isoform X6 |
| XM_038655061.1 | XP_038510989.1 | BDNF/NT-3 growth factors receptor isoform X8 |
| XM_038655054.1 | XP_038510982.1 | BDNF/NT-3 growth factors receptor isoform X1 |
| XM_038655056.1 | XP_038510984.1 | BDNF/NT-3 growth factors receptor isoform X3 |
| XM_038655057.1 | XP_038510985.1 | BDNF/NT-3 growth factors receptor isoform X4 |
NTRK2 Protein Structure
LRR_8: pfam13855 (91 - 149)
TPKR_C2: pfam16920 (150 - 194)
Ig: cl11960 (204 - 282)
Ig: cd00096 (213 - 217)
Ig: cd00096 (226 - 229)
Ig: cd00096 (244 - 251)
Ig: cd00096 (261 - 267)
Ig: cd00096 (275 - 278)
IgI_TrkB_d5: cd05855 (285 - 378)
IgI_TrkB_d5: cd05855 (285 - 293)
IgI_TrkB_d5: cd05855 (294 - 297)
IgI_TrkB_d5: cd05855 (300 - 308)
IgI_TrkB_d5: cd05855 (311 - 318)
IgI_TrkB_d5: cd05855 (321 - 324)
IgI_TrkB_d5: cd05855 (329 - 334)
IgI_TrkB_d5: cd05855 (340 - 348)
IgI_TrkB_d5: cd05855 (356 - 364)
IgI_TrkB_d5: cd05855 (367 - 375)
PTKc_TrkB: cd05093 (547 - 834)
- 0
- 200
- 400
- 600
- 800
- 838 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
BDNF/NT-3 growth factors receptor |
|
Recombinant NTRK2 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P73461 | TrkB Protein, Canine (HEK293, His) | XP_541264.2 (C32-H430) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P73576 | TrkB Protein, Canine (HEK293, Fc) | A0A8C0LGP8/XP_541264.2 (C32-H430) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Agents
- Approval
- Pre-clinical Phase
Approval
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-131003 | Taletrectinib | Inhibitor | 99.63% | Unkown |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS09631 | NTRK2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-131003A | Taletrectinib free base | Inhibitor | / | Unkown |
| HY-101977A | (R,S)-Selitrectinib | Inhibitor | / | Unkown |
| HY-E70870 | TRKB(NTRK2) Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-RS09632 | Ntrk2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS09633 | Ntrk2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P991098 | Anti-TrkB/NTRK2 Antibody | Inhibitor | / | Unkown |
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