NTRK2 - neurotrophic receptor tyrosine kinase 2 Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 484147 | Gene type: protein coding

About NTRK2

Primary_assembly 1: 74,755,372-75,083,341 reverse strand.ROS_Cfam_1.0:CM025100.1

This gene has 4 transcripts (splice variants), 288 orthologues and 54 paralogues.

mRNA	Protein	Name
XM_038655058.1	XP_038510986.1	BDNF/NT-3 growth factors receptor isoform X5
XM_038655060.1	XP_038510988.1	BDNF/NT-3 growth factors receptor isoform X7
XM_038655055.1	XP_038510983.1	BDNF/NT-3 growth factors receptor isoform X2
XM_038655059.1	XP_038510987.1	BDNF/NT-3 growth factors receptor isoform X6
XM_038655061.1	XP_038510989.1	BDNF/NT-3 growth factors receptor isoform X8
XM_038655054.1	XP_038510982.1	BDNF/NT-3 growth factors receptor isoform X1
XM_038655056.1	XP_038510984.1	BDNF/NT-3 growth factors receptor isoform X3
XM_038655057.1	XP_038510985.1	BDNF/NT-3 growth factors receptor isoform X4

LRR_8

TPKR_C2

IgI_TrkB_d5

PTKc_TrkB

Protein Preferred Names

Protein Names

BDNF/NT-3 growth factors receptor

neurotrophic tyrosine kinase receptor type 2

Cat. No.	Product Name	Accession	Purity
HY-P73461	TrkB Protein, Canine (HEK293, His)	XP_541264.2 (C32-H430)	≥95%
HY-P73576	TrkB Protein, Canine (HEK293, Fc)	XP_541264.2 (M1-H430)	≥95%

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-131003	Taletrectinib	Inhibitor	99.78%	Phase 2
HY-131003A	Taletrectinib free base	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS09631	NTRK2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS09632	Ntrk2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS09633	Ntrk2 Rat Pre-designed siRNA Set A	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	NTRK2	NCBI	NCBI:4915
Mus musculus	NTRK2	NCBI	NCBI:18212
Rattus norvegicus	NTRK2	NCBI	NCBI:25054

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