2. Gene
  3. Rps6ka3 - ribosomal protein S6 kinase A3 Gene

Rps6ka3 - ribosomal protein S6 kinase A3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1563860

Gene ID: 501560 | Gene type: protein coding

About Rps6ka3

Primary_assembly X: 35,517,306-35,623,207 reverse strand.mRatBN7.2:CM026994.1

This gene has 6 transcripts (splice variants), 252 orthologues, 7 paralogues and is associated with 16 phenotypes. Biased expression in Kidney (RPKM 164.9), Muscle (RPKM 141.8) and 9 other tissues.

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein kinase binding activity; and ribosomal protein S6 kinase activity. Predicted to be involved in several processes, including negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidyl-serine phosphorylation; and response to lipopolysaccharide. Predicted to be located in cytosol and nucleolus. Predicted to be active in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Lowry syndrome; intellectual disability; and non-syndromic X-linked intellectual disability 19. Orthologous to human RPS6KA3 (ribosomal protein S6 kinase A3). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka3 Products(1)

mRNA Protein Name
NM_001192004.3 NP_001178933.1 ribosomal protein S6 kinase alpha-3

Rps6ka3 Protein Structure

STKc_RSK_N

STKc_RSK_N: cd05582 (90 - 406)

STKc_RSK2_C

STKc_RSK2_C: cd14176 (420 - 758)

  • 0
  • 200
  • 400
  • 600
  • 759 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase alpha-3

ribosomal protein S6 kinase polypeptide 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148061 DB1113 99.28% Unkown
HY-150643 RSK2-IN-2 Inhibitor / Unkown
HY-150717 RSK2-IN-3 Inhibitor / Unkown
HY-RS12254 RPS6KA3 Human Pre-designed siRNA Set A / Unkown
HY-RS12255 Rps6ka3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12256 Rps6ka3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6ka3 NCBI NCBI:6197